Mastering the Unexpected in Oncology Trials: Turning Challenges into Triumphs

Oncology clinical trials are among the most complex in drug development – recruitment is slower, retention is harder, and unforeseen obstacles are the rule rather than the exception. At Pharma Clinical, we specialize in facing these challenges head-on with proactive, innovative solutions.

Recently, during a pivotal oncology trial in Israel, we encountered an external obstacle that threatened recruitment. Undeterred, Yafit Cohen, our Country Lead Monitor (CLM), leveraged her extensive network and expertise to craft a solution that kept the trial moving forward seamlessly. Despite the hurdles, recruitment and retention in Israel significantly outperformed many other countries.

“Our strategy wasn’t only about fixing the immediate issue,” Yafit explains. “It was about maintaining trust with stakeholders and showing we could manage oncology-specific challenges. Patient retention was notably higher in Israel – thanks to close monitoring, immediate availability, comprehensive site staff training, clear patient guidance, and proactive problem-solving, including medication supply issues. This level of support is rarely offered by large CROs, and it made the difference here.”

The results spoke for themselves. The sponsor highlighted Israel as a success story – not just for the numbers, but for the resilience, adaptability, and patient-centric approach we brought to the study.

In oncology clinical research, the true measure of success is overcoming the unexpected with agility and determination. Our story underlines this, reminding the industry that with the right team and mindset, no challenge is too great.

For sponsors and global CROs navigating oncology trials in Israel: don’t leave success to chance. Partner with Pharma Clinical, and together we will turn oncology challenges into milestones and achieve meaningful progress for patients.